In this paper we review Castagnino's contributions to the foundations ofquantum mechanics. First, we recall his work on quantum decoherence in closedsystems, and the proposal of a general framework for decoherence from which thephenomenon acquires a conceptually clear meaning. Then, we introduce hiscontribution to the hard field of the interpretation of quantum mechanics: themodal-Hamiltonian interpretation solves many of the interpretive problems ofthe theory, and manifests its physical relevance in its application to manytraditional models of the practice of physics. In the third part of this workwe describe the ontological picture of the quantum world that emerges from themodal-Hamiltonian interpretation, stressing the philosophical step toward adeep understanding of the reference of the theory.
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